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Thomas Prevot
  • Thomas Prevot

DAMONA Pharmaceuticals Appoints John Reilly as Chief Executive Officer
DAMONA Pharmaceuticals Appoints John Reilly as Chief Executive Officer 1200 627 Thomas Prevot

TORONTO, June 13, 2023— DAMONA Pharmaceuticals, a preclinical biopharmaceutical company focused on the discovery and development of first-in-class small molecules for the treatment and prevention of cognitive symptoms associated with brain disorders and aging, today announced the appointment of John Reilly as the company’s Chief Executive Officer and member of the Board of Directors. Mr.…

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  • Thomas Prevot

DAMONA’s development highlighted at the University of Toronto
DAMONA’s development highlighted at the University of Toronto 1000 730 Thomas Prevot

DAMONA Pharmaceuticals was recently highlighted in a news article, prepared by Ben Gane, for the University of Toronto. This article highlights the creation of Damona by CAMH (the Centre of Addiction and Mental Health in Toronto) and Dr. Etienne Sibille. Full Article In this article, you can learn about the company’s achievements that have attracted…

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  • Thomas Prevot

The Ontario Brain Institute invests $400,000 CAD in DAMONA
The Ontario Brain Institute invests $400,000 CAD in DAMONA 2023 774 Thomas Prevot

We are delighted to announce that the Ontario Brain Institute (OBI) is investing approximately $400,000 CAD in Damona Pharmaceuticals, to provide support to the company developing treatments for cognitive deficits in depression and other brain disorders. DAMONA’s team is excited to engage with OBI, and thank them for their support.

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  • Thomas Prevot

New Research Article: Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits
New Research Article: Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits 375 375 Thomas Prevot

Through a multicentered collaboration, joining experts from the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN), Yao and colleagues are presenting this new release, highlighting how depression impairs cortical inhibition and stimulus processing Find Article Cortical processing depends on finely tuned excitatory and inhibitory connections in neuronal microcircuits. Reduced inhibition by…

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  • Thomas Prevot

Living With Dementia – Dr. Sibille presents how his work can help (CTV Your Morning)
Living With Dementia – Dr. Sibille presents how his work can help (CTV Your Morning) 150 150 Thomas Prevot

LIVING WITH DEMENTIA – CTV Your Morning  https://www.youtube.com/watch?v=8AVa1frLbyA From CTV Your Morning On September 16th, 2021, CTV Your Morning presented a media piece about memory loss and how CAMH contributes to tackling this issue. It introduces Paul Leah, an individual that had a stroke more than 10 years ago, damaging a quarter of his brain. Paul now lives…

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  • Thomas Prevot

What could prevent suicide? – Read the piece highlighting Dr. Sibille’s research from TORONTO STAR
What could prevent suicide? – Read the piece highlighting Dr. Sibille’s research from TORONTO STAR 150 150 Thomas Prevot

What could prevent suicide? For CAMH and mental health advocates, it’s advances in research and treatment. Article on TORONTO STAR What could prevent suicide? For CAMH and mental health advocates, it’s advances in research and treatment. For decades, suicide and mental health were taboo topics in most social circles. Opening upabout personal struggles was often…

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  • Thomas Prevot

What Happens to Our Brains When We Get Depressed?
What Happens to Our Brains When We Get Depressed? 150 150 Thomas Prevot

The human brain, in all its complexity, is nearly impossible to model. Neuroscientists are trying anyway. Illustration by Jeremy Leung The WALRUS, Canadian general-interest magazine published a new piece on May 19th, 2021 about CAMH scientists working towards clarifying the impact of depression on our brain. The piece by writer Simon Lewsen, and beautifully illustrated by…

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  • Thomas Prevot

Making old brain cells feel young again
Making old brain cells feel young again 1399 1127 Thomas Prevot

Find out more about Dr. Sibille’s research at camh, and how it relates to Research & Development in AlphaCog. Link to Camh Website Long before the technology existed that allows CAMH scientists to observe what is actually going on in the living brain, none other than Dr. Sigmund Freud declared that the brains of people…

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  • Thomas Prevot

New Research Article shows Beneficial Effects of a New Drug in Transgenic Mouse Model with Cognitive Dysfunctions and Anxiety Phenotype
New Research Article shows Beneficial Effects of a New Drug in Transgenic Mouse Model with Cognitive Dysfunctions and Anxiety Phenotype 613 472 Thomas Prevot

The paper was published by Fee et al. in the International Journal of Neuropsychopharmacology. Patients suffering from mood and anxiety disorders often exhibit a deficit in brain inhibition. This deficit in brain inhibition is due do dysfunctional somatostatin (SST) cells, causing mood and cognitive symptoms in patients. Using transgenic mice in which the SST cell…

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  • Thomas Prevot

A new molecule shows efficacy at reversing brain atrophy observed during aging
A new molecule shows efficacy at reversing brain atrophy observed during aging 639 450 Thomas Prevot

Drs. Prevot, Sibille and Colleagues just published their finding in the Journal Cerebral Cortex, about a new molecule reversing brain atrophy and memory dysfunction observed during aging. During aging, our brain tends to slowly shrink in size due to neuronal shrinkage and reduced function. This phenomenon participates in the emergence of cognitive and memory deficits,…

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